Vagal Suppression Of Neurally-Induced Atrial Fibrillation

Professor Ardell has identified a novel means of preventing or blunting atrial fibrillation by modulating the neuronal network which controls the heart. Research to date has demonstrated that therapeutic potential of targeting cardiac neurons to modify…

Professor Ardell has identified a novel means of preventing or blunting atrial fibrillation by modulating the neuronal network which controls the heart. Research to date has demonstrated the therapeutic potential of targeting cardiac neurons to modify atrial arrhythmia and the ability of vagal nerve suppression to blunt atrial fibrillation that results from excessive neural inputs. Targeting the network of cardiac neurons that contribute to atrial fibrillation, therefore, represents a novel approach to treating AF. This novel therapeutic approach is innovative for its rapid therapeutic onset, ability to be rapidly reversed, and therapeutic memory (3 minutes of treatment can confer protection against AF for over 25 minutes).

Abstract

UCLA researchers in the Department of Cardiology have identified a novel mechanism for controlling atrial fibrillation via neuromodulation.

Website

https://techtransfer.universityofcalifornia.edu/NCD/28772.html?utm_source=AUTMGTP&utm_medium=webpage&utm_term=ncdid_28772&utm_campaign=TechWebsites

Advantages

  • A single point of treatment can modulate a wide range of neurons within the local heart nerve network
  • Rapid therapeutic onset and retains therapeutic memory, but is quickly reversible

Potential Applications

Treatment for atrial fibrillation

Contact Information

Name: UCLA Technology Development Group

Email: ncd@tdg.ucla.edu

Phone: 310.794.0558