Researchers at UCLA have developed a method to treat melanoma that resists conventional immune checkpoint blockade immunotherapy by using ferroptosis-inducing drugs. Ferroptosis is a type of cell death resulting from the accumulation of reactive oxygen species that degrade lipids in the cell membrane. De-differentiating cells, such as immunotherapy-resistant or kinase inhibitor-resistant melanoma, are highly susceptible to ferroptosis. Combination treatment with ferroptosis-inducing agents can be a valuable, new synergistic approach for overcoming resistance to melanoma therapy.
Abstract
Researchers in the Department of Physics have developed a method for detecting localized electrical breakdowns in high-power RF networks.
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Advantages
- Early detection
- Does not require taking the system apart
- No additional components required
- Detection in complex waveguides
Potential Applications
- Transmission lines
- Radar systems
- Electrical protective systems
- High-frequency protective circuits
Contact Information
Name: UCLA Technology Development Group
Email: ncd@tdg.ucla.edu
Phone: 310.794.0558