Self-Healing Elastomers

­Elastomers that enable rapid and repeatable self-healing properties in the absence of external stimuli and which can be tuned for mechanical, adhesive and degradable properties. Background: Self-healing elastomers that restore their properties a…

­Elastomers that enable rapid and repeatable self-healing properties in the absence of external stimuli and which can be tuned for mechanical, adhesive, and degradable properties. Background: Self-healing elastomers that restore their properties after damage hold great promise across a variety of industries and applications. Those that have been explored for engineering applications (e.g. flexible electrodes and self-healing paints) require harsh conditions (e.g. high temperatures and toxic catalysts) in order to exhibit their self-healing properties, which restricts their use in biomedical applications. Efforts to incorporate reversible self-healing functionality into soft polymer chains have mostly involved non-degradable polymers while those that are degradable do not possess the ability to properly self-heal at ambient physiologic conditions. As a result, the clinical use of self-healing elastomers has been limited to applications where biodegradability is not required (e.g. self-healing cement and fillers for orthopedic and dental applications, respectively). Technology Overview: This invention provides self-healing elastomers that can be modified to impart adhesive and/or biodegradable properties and/or tuned to adjust mechanical properties, which, as a whole, enable broad application potential. The elastomers of this invention possess the ability to repeatedly and rapidly self-repair physical damages at ambient conditions without the use of external stimuli. These elastomers have been used to prepare and test a biodegradable, self-healing vascular (arteriovenous) graft early cannulation following implantation, unlike traditional PTFE grafts that require a 4-week period prior to the first cannulation.

Advantages:

  • Highly tunable depending on the desired application
  • Do not require external stimuli to enable self-healing properties
  • Self-healing at physiologic temperature, where desired
  • Ability to repeatedly self-heal without limitations resulting from consumption of loaded agents

Applications:

  • Biomedical (wearable electronics, biosensors, self-healing electrodes, wound healing, etc.)
  • Industrial (coatings, adhesives, etc.)
  • Tissue engineering (vascular grafts, cardiac/vascular patches, etc.)
  • Drug delivery

Intellectual Property Summary: US Provisional Patent Application 63/255,012 filed October 13, 2021 Stage of Development: Preclinical Licensing Status: Available for licensing or collaboration.

Website

https://suny.technologypublisher.com/tech/Self-Healing_Elastomers

Contact Information

TTO Home Page: https://suny.technologypublisher.com

Name: Timothy Dee

Title: Associate Director

Email: tpdee@buffalo.edu

Phone: 716-645-8139