Improved Atomic-Resolution Guide for Drug Design

  • Provides insight into the structural basis for ligand binding, especially in extremely hydrophobic environments.
  • Key structural information on drug target of interest and ligand binding guides design of new, more potent therapeutic agents

Abstrato

This technology provides a method for generating precise atomic-level structural information on certain druggable targets to guide drug design. Enhancements to the crystallization process results in high-resolution structures of protein-ligand complexes that were previously unavailable in such detail. This information may then be used to advance research and development efforts, especially in drug discovery.

Informações de contato

Nome: Janie C Hurley

E-mail: jhurley@tamu.edu

Telefone: (979) 845-6337