Phosphodiesterase Inhibitor to Combat Mycobacterium Tuberculosis

Technology Readiness Level: 3 – Concept Validated through theory, siumulation, or modelsTechnology Validation: The researchers tested over 90,000 compounds for cyclic dinucleotide phosphodiesterase (CdnP) inhibition capability using high-throughput sc…
  • Technology Readiness Level: 3 - Concept Validated through theory, siumulation, or models
  • Technology Validation: The researchers tested over 90,000 compounds for cyclic dinucleotide phosphodiesterase (CdnP) inhibition capability using high-throughput screening (HTS) with the group's Coralyne assay; over 40% of the drugs had inhibitory capabili