Genes and Polypeptides of Neisseria Musculi that can be used to Evaluate Vaccines and Anti-Bacterial Compounds against Infection by Pathogenic Neisseria Species

A set of Neisseria musculi (Nmus) genes have been identified which promote Nmus infection and persistence in its natural host, the mouse. These genes have never been described before, so the in-host function of their encoded proteins is unknown. These …

A set of Neisseria musculi (Nmus) genes have been identified which promote Nmus infection and persistence in its natural host, the mouse. These genes have never been described before, so the in-host function of their encoded proteins is unknown. These genes are present in the human pathogenic Neisseria, N. meningitides, and N. gonorrhea. These genes and/or their encoded proteins are therefore potential targets for vaccines and antimicrobials against N. meningitides and N. gonorrhea.

Background:
The proposed technology can be potentially used to treat both N. meningitidis and N. gonorrhoeae by being an antimicrobial treatment and a vaccine possibility. The new genes identified to make it an extremely versatile proposition that would be extremely useful and convenient.

N. meningitidis can cause some serious illnesses including meningococcal disease. This disease can be extremely harmful to young adults and adolescents, necessitating the need for vaccination. The other application of this proposed technology would be developing a treatment for N. gonorrhoeae, which is extremely prevalent in the United States. In 2019, over 616,000 people were impacted and it continues to be a growing issue. Infection rates have increased by over 50% overall people from 2015-to 2019. It is an issue that could use some new treatment technology to help those and keep the serious cases to a minimum.

Applications:

  • N. meningitidis vaccines and antimicrobial treatment
  • N. gonorrhoeae antimicrobial treatment

Advantages:

  • New method
  • Possibly more effective
  • Better target in the body
  • Multiple applications

Website

https://arizona.technologypublisher.com/tech/Genes_and_Polypeptides_of_Neisseria_Musculi_that_can_be_used_to_Evaluate_Vaccines_and_Anti-Bacterial_Compounds_against_Infection_by_Pathogenic_Neisseria_Species
Contact Information

TTO Home Page: https://arizona.technologypublisher.com

Name: Tod McCauley

Title: Assistant Director of Licensing, CALS

Department: TLA

Email: todm@tla.arizona.edu

Phone: 520-621-9493