Professor Ardell has identified a novel means of preventing or blunting atrial fibrillation by modulating the neuronal network which controls the heart. Research to date has demonstrated the therapeutic potential of targeting cardiac neurons to modify atrial arrhythmia and the ability of vagal nerve suppression to blunt atrial fibrillation that results from excessive neural inputs. Targeting the network of cardiac neurons that contribute to atrial fibrillation, therefore, represents a novel approach to treating AF. This novel therapeutic approach is innovative for its rapid therapeutic onset, ability to be rapidly reversed, and therapeutic memory (3 minutes of treatment can confer protection against AF for over 25 minutes).
Abstract
UCLA researchers in the Department of Cardiology have identified a novel mechanism for controlling atrial fibrillation via neuromodulation.
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Advantages
- A single point of treatment can modulate a wide range of neurons within the local heart nerve network
- Rapid therapeutic onset and retains therapeutic memory, but is quickly reversible
Potential Applications
Treatment for atrial fibrillation
Contact Information
Name: UCLA Technology Development Group
Email: ncd@tdg.ucla.edu
Phone: 310.794.0558