Small Molecule Inhibitors of Cardiovascular and Renal Ectopic Calcification


UCLA researchers in the Department of Medicine have discovered that administration of small molecule inhibitors of ENPP1 or functional antagonists of PPi can substantially attenuate ectopic calcification. This suggests that ENPP1 and PPi can be potential pharmacological targets when developing therapeutics for pathological ectopic calcification.



These small molecules are the only drugs that have shown efficacy to retard or reverse ectopic calcification.

Contact Information

Name: UCLA Technology Development Group


Phone: 310.794.0558