SJ-21-0045 – Compounds that degrade GSPT1/IKZF1

  • PROTACs to degrade GSPT1/IKZF1
  • Treats Cancer (hematological malignancies, solid tumors).
  • Greater potency for degradation over existing small molecules

Abstract

Researchers at St. Jude created small molecules that target protein degradation of GSPT1/IKZF1 for the treatment of cancer (hematological malignancies, solid tumors). These compounds indicate greater potency for degradation over existing small molecules. We are seeking partners to commercialize these small molecules.

Contact Information

Name: Shawn A Hawkins

Email: shawn.hawkins@stjude.org

Phone: 901-595-5354