Patients who suffer from a broad range of disorders involving tissue degeneration – such as Parkinson’s disease, a myocardial infarction (heart attack), or liver failure – could potentially benefit from implantation of new healthy cells or engineered tissues to replace damaged or diseased ones, a process known as cell replacement therapy. Stem cells have the unique abilities to replicate indefinitely in an immature state and to differentiate into various types of cells found in the body. Therefore, stem cells can be harnessed as the cell source for such cell replacement and tissue engineering therapies. As such, systems and methods for scalable stem cell expansion and differentiation are of interest.
UC Berkeley researchers have developed thermoreversible polymers, hydrogel compositions comprising the thermoreversible polymers, as well as methods of making and using the thermoreversible polymers for use in cell replacement therapies.
Name: Terri Sale