RNA Hydrogel

Created from an RNA with unique sequence through self-assembly, this hydrogel has potential in a range of medical and research applications RSS.HDBackground> Background: < Hydrogels are water-saturated turgid materials used for a wide range of…
Created from an RNA with unique sequence through self-assembly, this hydrogel has potential in a range of medical and research applications RSS.HDBackground> Background: < Hydrogels are water-saturated turgid materials used for a wide range of applications such as tissue engineering scaffolds and drug delivery vehicles. Hydrogels are one of the most widely investigated and versatile technologies for drug delivery and tissue engineering applications, due to their tunable structure. These gels can also serve as selective filters or selective barriers for a broader range of permeability control. To date, all naturally occurring biomolecules are known to be capable of forming hydrogels or biocompatible hydrogels, with the exception of RNA. RNA has not been known previously to either possess the functional parts or modular sequence segments to form hydrogels by self-assembly. Technology Overview: This technology, developed by University at Albany researchers, is an RNA whose sequence contains two unique segments or motifs. This RNA has the unprecedented capacity to form hydrogel by self-assembly, due to the novel sequence motifs. The RNA molecule can be made from its DNA sequence template using enzymatic transcription. Advantages: Unique. This is the first case where RNA can self-assemble into hydrogel. Versatile. The uses of hydrogels in medical research are many and varied. The creation of RNA hydrogels may expand these uses to a range of potentially valuable and important applications. Applications: Tissue engineering Drug delivery platforms Cell culture scaffolds Wound dressing Intellectual Property Summary: Patented Stage of Development: This technology has been granted US Patent No. 10,731,165 RNA Hydrogels Licensing Potential: Development partner - Commercial partner - Licensing Licensing Status: This technology is available for licensing. This technology could be of significant interest to: Medical treatment facilities Pharmaceutical companies Medical research centers Educational institutions Additional Information:   Column3 biocompatible, biocompatible hydrogel, biological scaffold, biomaterial scaffold, cell culture, cell scaffold, cellular scaffold, dna sequence, drug delivery, drug delivery component, drug delivery platform, engineered RNA, gel, hydrogel, hydrogel formation, hydrogel scaffold, hydrogel synthesis, hydrogels, rna, rna synthesis, rna technology, rna transcription, self assembly, self-assembly, tissue engineering, tissue engineering scaffold, tissue scaffold, tissue-hydrogel complex, transcription, wound dressing, wound healing, wound-healing https://suny.technologypublisher.com/files/sites/adobestock_80319225.jpeg Inpart Image source