A robust method for non-covalently linking single biomolecules to an electrical circuit and reading biomolecular dynamics has been developed. This novel implementation utilizes carbon nanotubes and results in a very generalizable, high yield approach with an improved signal-to-noise ratio. This system also provides for higher information content and more straightforward analysis than current approaches.
Abstract:
A high-quality nanometer-scale electrical circuit with a single protein attached to a carbon nanotube allows for the detailed study of the kinetics and dynamics of single proteins.
Website:
Advantages:
Highly generalizable, high yield method providing an improved signal to noise ratio
Potential Applications:
Drug discovery, protein studies
Contact Information:
Name: Casie Kelly-Quintos
Email: casie.kelly@research.uci.edu
Phone: 949-824-2920