Nanoelectronic Circuits For Mechanistic Protein Studies And Drug Discovery

A robust method for non-covalently linking single biomolecules to an electrical circuit and reading biomolecular dynamics has been developed. This novel implementation utilizes carbon nanotubes and results in a very generalizable, high yield approach …

A robust method for non-covalently linking single biomolecules to an electrical circuit and reading biomolecular dynamics has been developed. This novel implementation utilizes carbon nanotubes and results in a very generalizable, high yield approach with an improved signal-to-noise ratio. This system also provides for higher information content and more straightforward analysis than current approaches.

Abstract:

A high-quality nanometer-scale electrical circuit with a single protein attached to a carbon nanotube allows for the detailed study of the kinetics and dynamics of single proteins.

Website:

https://techtransfer.universityofcalifornia.edu/NCD/22343.html?utm_source=AUTMGTP&utm_medium=webpage&utm_term=ncdid_22343&utm_campaign=TechWebsites

Advantages:

Highly generalizable, high yield method providing an improved signal to noise ratio

Potential Applications:

Drug discovery, protein studies

Contact Information:

Name: Casie Kelly-Quintos

Email: casie.kelly@research.uci.edu

Phone: 949-824-2920