Composition of tunable carbohydrate nucleic acid conjugates for enhanced liver and kidney-specific targeting

  • Technology addresses the need for targeted delivery of nucleic acids and other macro and small molecular drugs into the liver and kidney for various therapeutic and diagnostic applications
  • The use of technology led to PNA delivery to the liver, which resulted in desired therapeutic effects in mice. PNA delivered to mice kidneys showed retentions up to 72 h
  • Technology uses carbohydrate-based conjugates, which have been used safely in pharmaceutical formulations

Contact Information

Name: Amit Kumar

Email : a.kumar@uconn.edu

Phone: (860) 486-6938