19092 – 3D Endoscopy

Abstract
Endoscope that combines a scanning fiber endoscope and a low coherence interferometry system to generate a 3D surface/image profile

Advantages

In medical practice, radiological and endoscopic/optical imaging each supply complimentary and unique clinical information. Radiological imaging measures bulk tissue properties supplied in 3D spatial coordinates that accurately match those of the physical subject. However, it has insufficient contrast and resolution to identify clinically important mucosal information. Endoscopic optical imaging (i.e. white light, fluorescence and various forms of optical tomography) is invaluable for disease diagnosis and monitoring treatment response of mucosa} anatomy. However, such 2D optical images are spatially disconnected from the subject’s 3D spatial coordinates/anatomy or their spatial relationship may be inferred indirectly by the viewer.

From the clinical perspective, what is missing is the anatomical context and relationship of the endoscopy information with respect to the bulk tissue properties supplied by the radiological imaging. For many diseases in hollow organs such as the head and neck, gastrointestinal tract and lung, spatially accurate mapping of endoscopic imaging to bulk radiological imaging would improve diagnosis and treatment. Attempts to achieve such registration using tracking technologies and computer vision are inaccurate or difficult to implement in hollow organs. True 3D endoscopic imaging for hollow organs remains elusive; especially a version registered to standard radiological imaging that includes subsurface information.

This system combines an Optical Coherence Tomography (OCT) system with a Scanning Fiber Endoscope (SFE). The OCT laser is coupled into the single mode light delivery fiber used in the SFE. The OCT signal is collected by the light delivery fiber and sent to the OCT detection system. The OCT data collection follows the same spiral trajectory as used in the standard SFE image collection. The OCT software was modified to recover only the location of the object’s surface. The Time of Flight (TOF), measurements, from the modified OCT system, and white light images (from the SFE) are collected simultaneously, a 3D surface constructed and the RGB signals for each data point mapped onto its corresponding 3D surface point.

During procedures, a user would move the 3D endoscope through a subject collecting images at a high frame rate, then the series of images would be used to recreate a more complete 3D surface/image profile.

Contact Information

Name: Noah Schwartz

Email: Noah.Schwartz@uhnresearch.ca

Phone: 0000000000