Mucin secretion is regulated by purigenic agonists and inflammatory mediators. The SPOC1 cell line was derived from spontaneously immortalized rat tracheal epithelial secondary cultures. SPOC1 cells secrete mucin under the control of a P2u purinoceptor. SPOC1 cells are a valuable tool for the study of airway epithelial secretory cell differentiation, function and neoplastic progression, as well as the key molecular events underlying mucous production.
This cell line is available for distribution from Applied Biological Materials and can be found at https://www.abmgood.com/immortalized-rat-tracheal-epithelial-cells-spoc-1.html
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