Dual Microcatheter

­Dual Microcatheter Project Id: D2021-45 With increasing use of embolization in minimally invasive surgical procedures, the demand for microcatheters has increased exponentially and the growth rate is at 8%. Arteriovenous malformations (AVMs) are…

Dual Microcatheter

Project Id: D2021-45

With the increasing use of embolization in minimally invasive surgical procedures, the demand for microcatheters has increased exponentially and the growth rate is at 8%. Arteriovenous malformations (AVMs) are abnormal connections between arteries and veins in the brain or spine. The distinguishing feature of an AVM is that shunting occurs through a collection of tortuous dysmorphic vessels, referred to as a nidus. AVMs are difficult or dangerous to treat and may cause bleeding into or around the brain. Treatment for an AVM involves partial or complete closure of the AVM through embolization (blocking). Current treatments involving placement of either a 1.3” Fr or 1.7” Fr microcatheter in close approximation to the vascular malformation and administration of a liquid embolic agent into the malformation may be problematic at times as the embolic agent tends to reflux backward instead of moving distally into the lesion. To prevent this reflux and augment the distal penetration of the embolic agent, a “pressure cooker” technique is used. The pressure cooker technique involves the placement of another microcatheter proximal to the original treatment microcatheter and the administration of a liquid embolic agent from it. However, in many instances, this is not sufficient to prevent reflux of the embolic agent. Thus, there is a need in the art for new and improved devices and methods for accomplishing AVM embolization.

Invention Summary:

Researchers at the University of Toledo have developed a novel dual-lumen microcatheter by adding an additional proximal port that helps with better AVM glue penetration while minimizing the risk for reflux and allows for application of an embolic agent without the embolic agent approaching the normal vessels. Also provided is a method for using the catheter to apply an embolic agent in the inflow vessel between a normal vessel and an AVM nidus. The ability to administer the embolic agent in this manner minimizes the chances that the embolic agent will leak into the normal vessels that are not in need of treatment. Using the novel microcatheter for the application of an embolic agent and/or a sclerosant solution provides a way of effectively treating an AVM nidus without damaging or risking other vessels in proximity to where the embolic agent and/or sclerosant solution is released. Additionally, the microcatheter is equipped with an inflatable balloon that allows for a vessel to be blocked off to prevent a medication or treatment substance from flowing in the wrong direction such as away from an AVM nidus or malformations to be treated.

Applications:

Treatment of chronic disorders via surgery.

Advantages:

  • Novel tip for increased efficiency.
  • An inflatable balloon ensures the prevention of distal migration of the embolic agent delivered through the agent delivery holes.
  • An inflatable balloon prevents medication or treatment substances from flowing in the wrong direction.
  • A microcatheter prevents damage to the vessel once the embolic agent has been delivered.
  • Improved access to the procedural site.
  • Overcomes complex coronary interventions.

IP Status:

Patent Pending

Website

http://utoledo.technologypublisher.com/technology/46576

Contact Information

TTO Home Page: http://utoledo.technologypublisher.com

Name: Lokesh Mohan

Title: Licensing Associate

Department: Technology Transfer

Email: lokeshwar.mohan@utoledo.edu

Phone: 419-530-6231