10131 – Zwitterionic Polymer for Antiviral and Antibacterial Dual-Functional Coating

Improved materials that offer a long-term solution to fomite transmission.
  • Improved materials that offer a long-term solution to fomite transmission.

Abstract

Bacterial and fungal infection due to fomite transmission is ubiquitous in our life. Widely used surfaces like medical instruments, public facilities, industrial equipment, personal electronics, public transportation, are key in transferring the contagious diseases. There is a demand to develop antibacterial and antifungal surfaces that work under ambient temperature and pressure and aqueous conditions to mitigate the pathogen transmission. The ongoing pandemic has increased the demand to develop materials that can be uniformly applied to ubiquitous surfaces and deactivate the pathogen without the incubation period, therefore stopping the community spread.Researchers at Cornell University have developed imidazolium-based zwitterionic polymer that has antifungal, anti-bacterial and antifouling properties that can be conformally grown in different substrates without any solvent. Initial data with human coronavirus at ambient conditions shows contact-deactivation and adhesion repellent properties with surface coated with the zwitterionic polymer. The zwitterion destroys the spike protein of the coronavirus thus denaturizing the protein and reducing the adhesion of the protein by 97.4% on certain surfaces. On aqueous surfaces, the reduction in viral adhesion is attributed to strong hydration and charge-neutral nature of the surfaces. The polymer surfaces can also prevent viral proliferation in surfaces with high aspect ratio.

Website

https://cornell.flintbox.com/technologies/E656761D52E945AA9AC9C70A9E109ED1

Advantages

  • Coating is substrate independent.
  • Coating is conformal over nano/microstructure.
  • Triple protection against biofilm growth, fungal and bacterial infection.

Potential Applications

  • Antifungal, antibacterial, antifouling coating.

Contact Information

Name: Ryan Luebke

Email: rtl77@cornell.edu

Phone: 607-254-4483